ChemicalBook--->CAS DataBase List--->1143578-94-2

1143578-94-2

1143578-94-2 Structure

1143578-94-2 Structure
IdentificationBack Directory
[Name]

TAK 21d
[CAS]

1143578-94-2
[Synonyms]

TAK 21d
4-[4-(3,4-Difluorophenyl)-2-pyrimidinyl]-N-3-pyridazinyl-1-piperazinecarboxamide
1-Piperazinecarboxamide, 4-[4-(3,4-difluorophenyl)-2-pyrimidinyl]-N-3-pyridazinyl-
[Molecular Formula]

C19H17F2N7O
[MDL Number]

MFCD30182269
[MOL File]

1143578-94-2.mol
[Molecular Weight]

397.38
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

<7.95mg/ml in 1eq. HCl
[form ]

Solid
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

TAK 21d is a fatty acid amide hydroloase (FAAH) inhibitor.
[in vivo]

FAAH-IN-6 (compound 21d) (1-10 mg/kg; p.o.) shows significantly ameliorates tactile allodynia in a dose-dependent fashion in SNI-induced neuropathic pain rats model[1].
FAAH-IN-6 (3-10 mg/kg; p.o.) shows significantly ameliorates tactile allodynia of the ipsilateral hind paw in CFA-induced inflammatory pain model[1].

[storage]

Store at -20°C
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