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114772-55-3

114772-55-3 Structure

114772-55-3 Structure
IdentificationBack Directory
[Name]

4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile
[CAS]

114772-55-3
[Synonyms]

Losartan Impurity 8
1'-Biphenyl]-2-carbonitrile
Benzene,1,3,5-tribromo-2,4,10-trimethyl-
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan
4'-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1
2-[4-[[2-butyl-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzonitrile
4′-(2-butyl-4-chloro-5-hydroxyMethyliMidzole-1-ylMethyl)- biphenyl-2-carbonitrile
2-(4-{[2-Butyl-4-chloro-5-(hydroxymethyl)imidazolyl]methyl} phenyl)benzene carbonitrile
4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-carbonitrile
4’-[(2-butyl-4-chloro-5-hydroxymethyl)-1H-imidazol-1-yl)methyl]-[1,1’-Biphenyl]-2-carbonitrile
[1,1'-Biphenyl]-2-carbonitrile, 4'-[[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl]-
4'-[(2-BUTYL-4-CHLORO-5-HYDROXYMETHYL-1H-IMIDAZOL-1-YL)METHYL]-1,1'-BIPHENYL-2-CARBONITRILE 114772-55-3
[Molecular Formula]

C22H22ClN3O
[MDL Number]

MFCD16619233
[MOL File]

114772-55-3.mol
[Molecular Weight]

379.88
Chemical PropertiesBack Directory
[Melting point ]

157-158°C
[Boiling point ]

605.6±55.0 °C(Predicted)
[density ]

1.19
[storage temp. ]

Refrigerator
[solubility ]

DMSO (Slightly), Ethyl Acetate (Slightly)
[form ]

Solid
[pka]

13.66±0.10(Predicted)
[color ]

White to Off-White
Hazard InformationBack Directory
[Uses]

Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan is a derivative of Losartan Potassium (L470500), a an angiotensin II antagonist and is commonly used to significantly reduce risk of new onset atrial fibrillation and associated stroke in high-risk patients.
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