| Identification | Back Directory | [Name]
CB-7921220 | [CAS]
115453-99-1 | [Synonyms]
CB-7921220
CB-7921220
(CB7921220)
6-(4-Aminostyryl)picolinic acid
2-Pyridinecarboxylic acid, 6-[2-(4-aminophenyl)ethenyl]- | [Molecular Formula]
C14H12N2O2 | [MOL File]
115453-99-1.mol | [Molecular Weight]
240.26 |
| Chemical Properties | Back Directory | [Melting point ]
225-226 °C | [Boiling point ]
504.3±50.0 °C(Predicted) | [density ]
1.329±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 0.3 mg/ml | [form ]
A crystalline solid | [pka]
1.01±0.50(Predicted) | [color ]
Pink to red |
| Hazard Information | Back Directory | [Description]
CB-7921220 is an inhibitor of the adenylyl cyclase (AC) isoforms AC1 and AC6. It is selective, reducing AC1 and AC6 activity by 60% while having no effect on AC2 and AC5 in Sf9 membranes stimulated by forskolin when used at a concentration of 100 μM. | [Uses]
CB-7921220 is an adenylate cyclase inhibitor. | [References]
[1] Brand CS, et al. Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75. DOI:10.1124/jpet.113.208157 |
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BOC Sciences
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Energy Chemical
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ChemeGen
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