ChemicalBook--->CAS DataBase List--->1159408-62-4

1159408-62-4

1159408-62-4 Structure

1159408-62-4 Structure
IdentificationBack Directory
[Name]

L96.TEA
[CAS]

1159408-62-4
[Synonyms]

L96.TEA
GalnAc-L96 TEA
Triethylamine 4-[[(3R,5S)-1-[1-[[(2R,3R,4R,5R,6R)-3-Acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl]oxy]-16,16-bis[[3-[[3-[5-[[(2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl]oxy]pentanamido]propyl]amino]-3-oxopropoxy]methyl]-5,11,18-trioxo-14-oxa-6,10,17-triazanonacosan-29-oyl]-5-[[bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-3-pyrrolidinyl]oxy]-4-oxobutanoate
[Molecular Formula]

C121H179N11O45.C6H15N
[MOL File]

1159408-62-4.mol
[Molecular Weight]

2608.96
Chemical PropertiesBack Directory
[solubility ]

Acetonitrile: Soluble
[form ]

Solid
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

GalNAc-L96, a triantennary N-acetylgalactosamine (GalNAc), is a ligand of asialoglycoprotein receptor (ASGPR). GalNAc-L96 can be used to synthesize GalNAc-siRNA and can be used for oligonucleotide delivery[1].
[References]

[1] Anna Clua, et al. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes. Molecules. 2022 Jun 20;27(12):3944. DOI:10.3390/molecules27123944
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