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1163-67-3

1163-67-3 Structure

1163-67-3 Structure
IdentificationMore
[Name]

NAPHTHOL AS ACETATE
[CAS]

1163-67-3
[Synonyms]

2-ACETOXY-3-NAPHTHOIC ACID ANILIDE
2-HYDROXY-3-NAPHTHOIC ACID ANILIDE ACETATE
3-ACETOXY-2-NAPHTHANILIDE
3-ACETOXY-2-NAPHTHOIC ACID ANILIDE
3-(ACETYLOXY)-N-PHENYL-2-NAPHTHALENECARBOXAMIDE
3-HYDROXY-2-NAPHTHOYLANILIDE ACETATE
ACETYL NAPHTHOL AS
NAPHTHOL AS ACETATE
2-(N-phenylcarbamoyl)-3-naphthyl acetate
NAPHTHOL AS-ACETATE FOR HISTOLOGY
NAPHTHOL-AS-ACETATE extrapure
3-Acetoxy-N-phenyl-2-naphthamide
3-Acetyloxy-2-naphthoic acid anilide
Acetic acid 3-(phenylcarbamoyl)naphthalen-2-yl ester
[EINECS(EC#)]

214-608-0
[Molecular Formula]

C19H15NO3
[MDL Number]

MFCD00004095
[Molecular Weight]

305.33
[MOL File]

1163-67-3.mol
Chemical PropertiesBack Directory
[Melting point ]

160-162°C
[Boiling point ]

424.6±28.0 °C(Predicted)
[density ]

1.271±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[form ]

powder to crystal
[pka]

12.67±0.70(Predicted)
[color ]

White to Light yellow
[Sensitive ]

Moisture Sensitive
[CAS DataBase Reference]

1163-67-3(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi,F
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
R34:Causes burns.
R11:Highly Flammable.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37:Wear suitable gloves .
S36:Wear suitable protective clothing .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S16:Keep away from sources of ignition-No smoking .
[HS Code ]

2924.29.3600
Hazard InformationBack Directory
[Uses]

Naphthol AS Acetate(3-Acetoxy-2-naphthanilide) is a reactive chemical that reacts with basic dyes, crosslinkers, and other compounds. It has been used in the treatment of lymphocytic leukemia cells in vitro.
[Application]

3-Acetoxy-2-naphthanilide also inhibits the enzyme activities of acetylcholinesterase and phosphatases, suggesting that it may be useful for treating myelogenous leukemias. 3-Acetoxy-2-naphthanilide is also used to dye agarose gels in order to visualize DNA bands during electrophoresis.
[Purification Methods]

Recrystallise it from hot MeOH and dry in vacuo over P2O5. It has m 252o after sublimation at 210-215o. It is slightly soluble in AcOH, EtOH, CHCl3 or *C6H6. It is a fluorogenic substrate for albumin esterase activity. [Chen & Scott Anal Lett 17 857 1984.] At 320nm it has fluorescence at 500nm. ex em [Brass & Sommer Chem Ber 61 1000 1928, Beilstein 12 II 260, 12 III 960, 12 IV 923.]
Spectrum DetailBack Directory
[Spectrum Detail]

NAPHTHOL AS ACETATE(1163-67-3)MS
NAPHTHOL AS ACETATE(1163-67-3)1HNMR
NAPHTHOL AS ACETATE(1163-67-3)13CNMR
NAPHTHOL AS ACETATE(1163-67-3)IR1
NAPHTHOL AS ACETATE(1163-67-3)IR2
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

Naphthol AS acetate, 98%(1163-67-3)
[Sigma Aldrich]

1163-67-3(sigmaaldrich)
[TCI AMERICA]

3-Acetoxy-2-naphthanilide,>98.0%(N)(1163-67-3)
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