ChemicalBook--->CAS DataBase List--->117592-45-7

117592-45-7

117592-45-7 Structure

117592-45-7 Structure
IdentificationBack Directory
[Name]

alpha-Casozepine
[CAS]

117592-45-7
[Synonyms]

Lactium
alpha-Casozepine
[Molecular Formula]

C60H94N14O16
[MOL File]

117592-45-7.mol
[Molecular Weight]

1267.47
Chemical PropertiesBack Directory
[density ]

1.37±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

3.34±0.10(Predicted)
[color ]

White to off-white
[Sequence]

Tyr-Leu-Gly-Tyr-Leu-Glu-Gln-Leu-Leu-Arg
Hazard InformationBack Directory
[Uses]

α-Casozepine is a bioactive peptide derived from the α protein S1 casein in milk and has an affinity for γ-aminobutyric acid (GABA) receptors in the brain. α-Casozepine has anti-anxiety effects[1][2].
[References]

[1] Miclo L, et al. Characterization of alpha-casozepine, a tryptic peptide from bovine alpha(s1)-casein with benzodiazepine-like activity. FASEB J. 2001 Aug;15(10):1780-2. DOI:10.1096/fj.00-0685fje
[2] Landsberg G, et al Therapeutic effects of an alpha-casozepine and L-tryptophan supplemented diet on fear and anxiety in the cat. J Feline Med Surg. 2017 Jun;19(6):594-602. DOI:10.1177/1098612X16669399
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