| Identification | Back Directory | [Name]
XX-650-23 | [CAS]
117739-40-9 | [Synonyms]
XX-650-23
2-Naphthalenecarboxamide, N-(4-cyanophenyl)-3-hydroxy- | [Molecular Formula]
C18H12N2O2 | [MDL Number]
MFCD00142927 | [MOL File]
117739-40-9.mol | [Molecular Weight]
288.3 |
| Chemical Properties | Back Directory | [Boiling point ]
454.0±30.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
8?+-.0.40(Predicted) | [color ]
Off-white to yellow |
| Hazard Information | Back Directory | [Uses]
XX-650-23 is a potent CREB inhibitor. XX-650-23inhibits CREB function through disruption of CBP-CREB interaction.?XX-650-23 can be used for AML research[1]. | [References]
[1] B Mitton, et al. Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cells. Leukemia. 2016 Dec;30(12):2302-2311. DOI:10.1038/leu.2016.139 |
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