| Identification | Back Directory | [Name]
2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside | [CAS]
118373-61-8 | [Synonyms]
2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine
2-Amino-6-chloropurine-9-β-D-(2’-deoxy-3’,5’-di-O-benzoyl-2’-fluoro)arabinoriboside
2-AMino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-β-D-arabinofuranosyl)-9H-purine
9H-Purin-2-amine, 6-chloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
2-Amino-6-chloropurine-9-beta-d-(2'-deoxy-3',5'-di-o-benzoyl-2'-fluoro)arabinoriboside
2-AMino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside
6-Chloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-2-amine | [Molecular Formula]
C24H19ClFN5O5 | [MDL Number]
MFCD25542488 | [MOL File]
118373-61-8.mol | [Molecular Weight]
511.89 |
| Chemical Properties | Back Directory | [Melting point ]
89-93 °C(Solvent: Ethanol) | [Boiling point ]
735.1±70.0 °C(Predicted) | [density ]
1.58±0.1 g/cm3(Predicted) | [pka]
1.69±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
2-Amino-6-chloropurine -9-beta-D-(2’-deoxy-3’,5’-di-O-benzoyl-2’-fluoro)arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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