| Identification | Back Directory | [Name]
Butanedioic acid, compd. with N-[(3-endo)-8-[[4-(thiazolo[4,5-b]pyridin-2-yloxy)phenyl]methyl]-8-azabicyclo[3.2.1]oct-3-yl]acetamide (1:) | [CAS]
1191044-47-9 | [Synonyms]
Butanedioic acid, compd. with N-[(3-endo)-8-[[4-(thiazolo[4,5-b]pyridin-2-yloxy)phenyl]methyl]-8-azabicyclo[3.2.1]oct-3-yl]acetamide (1:) |
| Hazard Information | Back Directory | [Uses]
JNJ-40929837 succinate is a selective and orally active LTA4H (leukotriene A4 hydrolase) inhibitor. JNJ-40929837 succinate effectively inhibits aminopeptidase activity and causes serum accumulation of Pro-Gly-Pro. JNJ-40929837 succinate can be used in asthma research[1]. | [References]
[1] Low CM, et al. The development of novel LTA4H modulators to selectively target LTB4 generation. Sci Rep. 2017 Mar 17;7:44449. DOI:10.1038/srep44449 |
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