| Identification | Back Directory | [Name]
3-Quinolinecarboxaldehyde, 6-broMo- | [CAS]
1196155-68-6 | [Synonyms]
6-broMo-3-Quinolinecarboxaldehyde
3-Quinolinecarboxaldehyde, 6-broMo- | [Molecular Formula]
C10H6BrNO | [MDL Number]
MFCD13190233 | [MOL File]
1196155-68-6.mol | [Molecular Weight]
236.06 |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,2-8°C | [Appearance]
Light yellow to green yellow Solid | [InChI]
InChI=1S/C10H6BrNO/c11-9-1-2-10-8(4-9)3-7(6-13)5-12-10/h1-6H | [InChIKey]
PCHCYMZZDAUVQB-UHFFFAOYSA-N | [SMILES]
N1C2C(=CC(Br)=CC=2)C=C(C=O)C=1 |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 6-bromoquinoline-3-carbaldehyde from (6-bromoquinolin-3-yl)methanol: (6-bromoquinolin-3-yl)methanol (716 mg, 2.70 mmol) was dissolved in dichloromethane (9 mL), manganese dioxide (705 mg, 8.12 mmol) was added, and the reaction was stirred at 20°C for 2 days. After completion of the reaction, the mixture was filtered through diatomaceous earth and the filtrate was concentrated under reduced pressure to afford the target product 6-bromoquinoline-3-carbaldehyde (577 mg, 63% yield). | [References]
[1] Patent: WO2011/131741, 2011, A1. Location in patent: Page/Page column 92
[2] Patent: US2012/94976, 2012, A1. Location in patent: Page/Page column 58 |
|
|