| Identification | Back Directory | [Name]
Vapendavir (diphosphate) | [CAS]
1198151-75-5 | [Synonyms]
BTA798 diphosphate
Vapendavir (diphosphate) | [Molecular Formula]
C21H29N4O7P | [MDL Number]
MFCD32689564 | [MOL File]
1198151-75-5.mol | [Molecular Weight]
480.46 |
| Hazard Information | Back Directory | [Uses]
Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2]. | [References]
[1] Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2. DOI:10.1128/AAC.03328-14
[2] Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5. DOI:10.1128/AAC.01375-15 |
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