| Identification | Back Directory | [Name]
GPAT-IN-1 | [CAS]
1204347-51-2 | [Synonyms]
GPAT-IN-1 3′-Chloro-4-[(octylsulfonyl)amino][1,1′-biphenyl]-3-carboxylic acid | [Molecular Formula]
C21H26ClNO4S | [MOL File]
1204347-51-2.mol | [Molecular Weight]
423.95 |
| Chemical Properties | Back Directory | [Melting point ]
133-134 °C | [Boiling point ]
580.4±60.0 °C(Predicted) | [density ]
1.264±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
3.22±0.36(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
GPAT-IN-1 is a glycerol-3-phosphate acyltransferase (GPAT) inhibitor with an IC50 value of 8.9 μM. GPAT-IN-1 can be used for the research of obesity[1]. | [References]
[1] Outlaw VK, et al. Design, Synthesis, and Evaluation of 4- and 5-Substituted o-(Octanesulfonamido)benzoic Acids as Inhibitors of Glycerol-3-Phosphate Acyltransferase. Medchemcomm. 2014;5(6):826-830. DOI:10.1039/C4MD00126E |
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