| Identification | Back Directory | [Name]
N-[(1,1-Dimethylethoxy)carbonyl]-L-methionyl-L-α-aspartylglycyl-L-cysteinyl-L-α-glutamyl-L-leucine | [CAS]
1206604-29-6 | [Synonyms]
N-[(1,1-Dimethylethoxy)carbonyl]-L-methionyl-L-α-aspartylglycyl-L-cysteinyl-L-α-glutamyl-L-leucine | [Molecular Formula]
C30H50N6O13S2 | [MOL File]
1206604-29-6.mol | [Molecular Weight]
766.88 |
| Chemical Properties | Back Directory | [Boiling point ]
1185.1±65.0 °C(Predicted) | [density ]
1.322±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
3.34±0.10(Predicted) | [color ]
White to off-white | [Sequence]
{t-Boc}-Met-Asp-Gly-Cys-Glu-Leu |
| Hazard Information | Back Directory | [Uses]
Box5 is a potent Wnt5a antagonist. Box5 inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca2+ release. Box5 inhibits cell migration. Box5 has the potential for the research of melanoma[1]. | [References]
[1] Jenei V, et al. A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasion. Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19473-8. DOI:10.1073/pnas.0909409106 |
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Fuan Bio
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15002819872 |
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fuanbio.com |
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