| Identification | Back Directory | [Name]
2-chloro-5-aminomethylthiazole | [CAS]
120740-08-1 | [Synonyms]
2-Chloro-5-Aomethylthiazole
2-chloro-5-aminomethylthiazole
5-Aminomethyl-2-chlorothiazole
5-ThiazoleMethanaMine, 2-chloro-
2-Chloro-5-thiazoleMethanaMine HCl
(2-chloro-1,3-thiazol-5-yl)MethanaMine | [Molecular Formula]
C4H5ClN2S | [MDL Number]
MFCD08705904 | [MOL File]
120740-08-1.mol | [Molecular Weight]
148.61 |
| Chemical Properties | Back Directory | [Melting point ]
121 °C | [Boiling point ]
274.7±32.0 °C(Predicted) | [density ]
1.427±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Oil | [pka]
7.68±0.29(Predicted) | [color ]
Colourless to Yellow | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
(2-Chlorothiazol-5-yl)methanamine is a metabolite of Thiamethoxam (T344180), a neonicotinoid insecticide. | [Synthesis]
General procedure for the synthesis of (2-chlorothiazol-5-yl)methanamine using 2-((2-chlorothiazol-5-yl)methyl)isodihydroindole-1,3-dione as starting material: 25.3 g of the above off-white solid and 150 mL of ethanol were added to a 250 mL three-necked flask in a unit equipped with a magnetic stirrer, a condenser tube and a drying tube. 9.1 g of hydrazine hydrate was slowly added dropwise to the reaction system. Subsequently, the reaction mixture was heated to reflux for 4-6 hours. Upon completion of the reaction, the solvent was evaporated under reduced pressure to afford 9.1 g of (2-chlorothiazol-5-yl)methylamine, the product was in the form of an orange oil. | [References]
[1] Patent: US2015/51402, 2015, A1. Location in patent: Page/Page column 0075 |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
NovoChemy Ltd.
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86-(0)21-31261262 373522135 |
| Website: |
www.novochemy.com |
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