| Identification | Back Directory | [Name]
(+/-)-Epicatechin -[13C3] | [CAS]
1217780-28-3 | [Synonyms]
13C3]-Catechin
(+-)-Epicatechin -[13C3]
(+/-)-Epicatechin -[13C3]
(+/-)-Catechin-[13C3]Gallate
(+/-)-Catechin-[13C3] Gallate
(+/-)-EPICATECHIN (CP 97% ) (2,3,4-13C3 ,99%)
(+/-)-CATECHIN GALLATE(2,3,4-13C3, 99%) (CP 97% )
(+/-)-CATECHIN GALLATE (2,3,4-13C3, 99%) (CP 97% )
cis-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol | [Molecular Formula]
C15H14O6 | [MOL File]
1217780-28-3.mol | [Molecular Weight]
293.295 |
| Hazard Information | Back Directory | [Uses]
(±)-Epicatechin-13C3 is the 13C labeled (±)-Epicatechin. (-)-Epicatechin (HY-N0001) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB[1]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40(2):173-9. DOI:10.1207/S15327914NC402_14
[3] Shay J, et al. Molecular Mechanisms and Therapeutic Effects of (-)-Epicatechin and Other Polyphenols in Cancer, Inflammation, Diabetes, and Neurodegeneration. Oxid Med Cell Longev. 2015;2015:181260. DOI:10.1155/2015/181260
[4] Nogueira L, et al. (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J Physiol. 2011 Sep 15;589(Pt 18):4615-31. DOI:10.1113/jphysiol.2011.209924 |
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Entegris, Inc.
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https://www.entegris.com |
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TargetMol
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www.targetmol.cn/ |
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