| Identification | Back Directory | [Name]
KR-12 (human) | [CAS]
1218951-51-9 | [Synonyms]
KR-12 (human)
KR-12 amide (human)
Antibacterial Protein LL-37 amide (human) (18-29)
H-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-NH2
Antibacterial Protein LL-37 aMide (huMan) (18-29), LL-37 (18-29), LL37 (18-29), CAMP (18-29)
KR-12 amide (human)/Antibacterial Protein LL-37 amide (human) (18-29), LL-37 (18-29), LL37 (18-29), CAMP (18-29)
L-Lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-argininamide | [Molecular Formula]
C71H127N25O15 | [MOL File]
1218951-51-9.mol | [Molecular Weight]
1570.93 |
| Chemical Properties | Back Directory | [density ]
1.40±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.19±0.10(Predicted) | [color ]
White to off-white | [Sequence]
H-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-NH2 |
| Hazard Information | Back Directory | [Uses]
KR-12 human is an active segment of LL-37, which exhibits antimicrobial activity against gram-negative bacteria. KR-12 human inhibits E. coli K-12 with MIC of 66 μM[1]. | [References]
[1] Epand RF, et al., Lipid segregation explains selective toxicity of a series of fragments derived from the human cathelicidin LL-37. Antimicrob Agents Chemother. 2009 Sep;53(9):3705-14. DOI:10.1128/AAC.00321-09 |
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