| Identification | Back Directory | [Name]
ALLOFERON 1 | [CAS]
347884-61-1 | [Synonyms]
Alloferon
ALLOFERON 1
Alloferon - in acetate salt
HIS-GLY-VAL-SER-GLY-HIS-GLY-GLN-HIS-GLY-VAL-HIS-GLY
H-HIS-GLY-VAL-SER-GLY-HIS-GLY-GLN-HIS-GLY-VAL-HIS-GLY-OH
Glycine, L-histidylglycyl-L-valyl-L-serylglycyl-L-histidylglycyl-L-glutaminyl-L-histidylglycyl-L-valyl-L-histidyl- | [Molecular Formula]
C52H76N22O16 | [MDL Number]
MFCD06656080 | [MOL File]
347884-61-1.mol | [Molecular Weight]
1265.3 |
| Chemical Properties | Back Directory | [Boiling point ]
2089.9±65.0 °C(Predicted) | [density ]
1.422±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.18±0.10(Predicted) | [color ]
White to off-white | [Sequence]
His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly | [Cosmetics Ingredients Functions]
SKIN CONDITIONING - EMOLLIENT
SKIN PROTECTING
BLEACHING |
| Hazard Information | Back Directory | [Uses]
Alloferon 1 is an antiviral and antitumoral peptide. Alloferon 1 stimulates natural cytotoxicity of human peripheral blood lymphocytes. Alloferon 1 also induces IFN synthesis, and enhances antiviral and antitumor resistance in mice. Alloferon 1 also shows anti-inflammatory activity in λ-carrageenan-induced paw edema model. Alloferon 1 can be isolated from the blood of the blow fly Calliphora vicina (Diptera)[1][2][3]. | [References]
[1] Chernysh S, et al. Antiviral and antitumor peptides from insects. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12628-32. DOI:10.1073/pnas.192301899
[2] Zhang X, et al. Alloferon-1 ameliorates acute inflammatory responses in λ-carrageenan-induced paw edema in mice. Sci Rep. 2022 Oct 6;12(1):16689. DOI:10.1038/s41598-022-20648-z |
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