| Identification | Back Directory | [Name]
Urea, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-(1H-pyrazol-4-yl)phenyl]-N'-(phenylmethyl)- | [CAS]
1219721-78-4 | [Synonyms]
ROCKIND2
ROCK-IN-D2
ROCK IN D2
ROCK inhibitor D2
ROCK-inhibitor-D2
Urea, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-(1H-pyrazol-4-yl)phenyl]-N'-(phenylmethyl)- | [Molecular Formula]
C22H28N6O | [MOL File]
1219721-78-4.mol | [Molecular Weight]
392.51 |
| Hazard Information | Back Directory | [Description]
ROCK-IN-D2 is a potent and selective ROCK inhibitor. | [Uses]
ROCK-IN-D2 is a potent and selective ROCK inhibitor[1]. | [References]
[1] Ding Mei, et al. Discovery of potent and selective urea-based ROCK inhibitors: Exploring the inhibitor’s potency and ROCK2/PKA selectivity by 3D-QSAR, molecular docking and molecular dynamics simulations.Bioorg Med Chem. 2015 May 15;23(10):2505-17. DOI:10.1016/j.bmc.2015.03.047 |
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