| Hazard Information | Back Directory | [Description]
L 156373 is an oxytocin antagonist from Streptomyces silvensis. | [Uses]
L 156373 is a potent oxytocin receptor antagonist with Ki value of 150 nM[1][2]. | [References]
[1] Elbatrawi YM, et al. Total Synthesis of L-156,373 and an oxoPiz Analogue via a Submonomer Approach. Org Lett. 2018 May 4;20(9):2707-2710. DOI:10.1021/acs.orglett.8b00912
[2] Pettibone DJ, et al. A structurally unique, potent, and selective oxytocin antagonist derived from Streptomyces silvensis. Endocrinology. 1989 Jul;125(1):217-22. DOI:10.1210/endo-125-1-217 |
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