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1225383-40-3

1225383-40-3 Structure

1225383-40-3 Structure
IdentificationBack Directory
[Name]

PROTAC CRABP-II Degrader-1
[CAS]

1225383-40-3
[Synonyms]

PROTAC CRABP-II Degrader-1
Retinoic acid, 4-[[[(11S,14S,15R)-15-amino-14-hydroxy-11-(2-methylpropyl)-2,10,13-trioxo-16-phenyl-6,9-dioxa-3,12-diazahexadec-1-yl]oxy]imino]-, (4E)-
[Molecular Formula]

C42H60N4O9
[MDL Number]

MFCD32062705
[MOL File]

1225383-40-3.mol
[Molecular Weight]

764.95
Chemical PropertiesBack Directory
[density ]

1.15±0.1 g/cm3(Predicted)
[pka]

4.73±0.33(Predicted)
Hazard InformationBack Directory
[Uses]

PROTAC CRABP-II Degrader-1 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on IAP ligand[1].
[References]

[1] Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176. DOI:10.1016/j.csbj.2019.01.006
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