| Identification | Back Directory | [Name]
LCL521 | [CAS]
1226851-11-1 | [Synonyms]
LCL521
Glycine, N,N-dimethyl-, 1,1'-[(1R,2R)-1-(4-nitrophenyl)-2-[(1-oxotetradecyl)amino]-1,3-propanediyl] ester | [Molecular Formula]
C31H52N4O7 | [MDL Number]
MFCD31813617 | [MOL File]
1226851-11-1.mol | [Molecular Weight]
592.77 |
| Chemical Properties | Back Directory | [Boiling point ]
697.4±55.0 °C(Predicted) | [density ]
1.093±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:150.0(Max Conc. mg/mL);253.05(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);168.7(Max Conc. mM) | [form ]
Oil | [pka]
14.18±0.46(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
LCL521 is an acid ceramidase (ACDase) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase (ASMase)[1]. | [References]
[1] Bai A, et al. Targeting (cellular) lysosomal acid ceramidase by B13: design, synthesis and evaluation of novel DMG-B13 ester prodrugs. Bioorg Med Chem. 2014 Dec 15;22(24):6933-44. DOI:10.1016/j.bmc.2014.10.025 |
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| Company Name: |
Wuhan Topule
|
| Tel: |
+86-02787215551 +86-19945035818 |
| Website: |
http://www.topule.com/ |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|