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1226855-28-2

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1226855-28-2 Structure

1226855-28-2 Structure
IdentificationBack Directory
[Name]

DSP-0565
[CAS]

1226855-28-2
[Synonyms]

DSP-0565
[1,1'-Biphenyl]-2-acetamide, 2'-fluoro-
[Molecular Formula]

C14H12FNO
[MDL Number]

MFCD32067898
[MOL File]

1226855-28-2.mol
[Molecular Weight]

229.25
Chemical PropertiesBack Directory
[Boiling point ]

435.7±38.0 °C(Predicted)
[density ]

1.190±0.06 g/cm3(Predicted)
[pka]

16.12±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

DSP-0565 (compound 17a) is a strong, broad-spectrum anti-epileptic agent (AED) candidate with unique GABAergic function. DSP-0565 shows anti-convulsant activity in various models (scPTZ, MES, 6 Hz and amygdala kindling) with good safety margin[1].
[References]

[1] Tanaka T, et al. Identification of 2-(2'-fluoro-[1,1'-biphenyl]-2-yl)acetamide as a Sodium Valproate-like broad spectrum anti-epileptic drug candidate. Bioorg Med Chem Lett. 2019 Jan 15;29(2):138-142. DOI:10.1016/j.bmcl.2018.12.014
Spectrum DetailBack Directory
[Spectrum Detail]

DSP-0565(1226855-28-2)1HNMR
1226855-28-2 suppliers list
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