ChemicalBook--->CAS DataBase List--->122799-38-6

122799-38-6

122799-38-6 Structure

122799-38-6 Structure
IdentificationMore
[Name]

2'-DEOXY-2'-FLUOROTHYMIDINE
[CAS]

122799-38-6
[Synonyms]

1-(2'-DEOXY-2'-FLUORO-BETA-D-RIBOFURANOSYL)-5-METHYLURACIL
2,4(1H,3H)-PYRIMIDINENONE, 1(2-DEOXY-2-FLUORO-BETA-D-RIBOFURANOSYL)-5-METHYL
2'-DEOXY-2'-FLUORO-5-METHYLURIDINE
2'-DEOXY-2'-FLUOROTHYMIDINE
5-METHYL-2'-FLUORO-D-URIDINE
5-METHYL-2'-FLUOROURACIL
2'-Fluoro-2'-deoxythymidine
[Molecular Formula]

C10H13FN2O5
[MDL Number]

MFCD03788702
[Molecular Weight]

260.22
[MOL File]

122799-38-6.mol
Chemical PropertiesBack Directory
[Melting point ]

185-186 °C
[density ]

1.55±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

9.55±0.10(Predicted)
[color ]

White to off-white
[CAS DataBase Reference]

122799-38-6(CAS DataBase Reference)
Safety DataBack Directory
[HS Code ]

29389090
Hazard InformationBack Directory
[Chemical Properties]

White to off-white powder
[Uses]

2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine), a bioisostere of both thymidine (TdR) and methyluridine, is a putative highly selective substrate for thymidine kinase type 2 (TK2)[1].
[References]

[1] Wiebe LI, et al. Biochemistry and biology of 2'-Fluoro-2'-deoxythymidine (FT), a putative highly selective substrate for thymidine kinase type 2 (TK2). Curr Radiopharm. 2012 Jan;5(1):38-46. DOI:10.2174/1874471011205010038
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