ChemicalBook--->CAS DataBase List--->123-41-1

123-41-1

123-41-1 Structure

123-41-1 Structure
IdentificationMore
[Name]

Choline hydroxide
[CAS]

123-41-1
[Synonyms]

(2-HYDROXYETHYL)TRIMETHYLAMMONIUM HYDROXIDE
CHOLINE
CHOLINE BASE
CHOLINE HYDROXIDE
L-URIDINE
2-hydroxy-n,n,n-trimethyl-ethanaminiuhydroxide
bursine
choline,solution
fagine
gossypine
sincaline
sinkalin
sinkaline
vidine
Choline hydroxide solution
Choline water solution
CHOLINE HYDROXIDE, 45 WT. % SOLUTION IN METHANOL
CHOLINE HYDROXIDE, 20 WT. % SOLUTION IN WATER
CHOLINE HYDROXIDE, 50 WT. % SOLUTION IN WATER
CHOLINE SOLUTION, ~45% IN METHANOL
[EINECS(EC#)]

204-625-1
[Molecular Formula]

C5H15NO2
[MDL Number]

MFCD00002831
[Molecular Weight]

121.18
[MOL File]

123-41-1.mol
Chemical PropertiesBack Directory
[Appearance]

colorless to tan viscous solution
[Melting point ]

236~239℃
[density ]

1.09 g/mL at 20 °C
[vapor pressure ]

28.284hPa at 25℃
[refractive index ]

n20/D 1.4304
[Fp ]

92 °F
[storage temp. ]

2-8°C
[solubility ]

Water (easy), ethanol (difficult to dissolve (1-pentanol)), ether (insoluble)
[form ]

Granular Powder
[pka]

13.9(at 25℃)
[color ]

White
[Stability:]

Stable. Combustible. Incompatible with strong oxidizing agents.
[Water Solubility ]

miscible
[Merck ]

2204
[InChI]

1S/C5H14NO.H2O/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H2/q+1;/p-1
[InChIKey]

KIZQNNOULOCVDM-UHFFFAOYSA-M
[SMILES]

[OH-].C[N+](C)(C)CCO
[LogP]

-2.25 at 25℃
[CAS DataBase Reference]

123-41-1(CAS DataBase Reference)
[EPA Substance Registry System]

123-41-1(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Corrosion (GHS05)
GHS05
[Signal word ]

Danger
[Hazard statements ]

H314
[Precautionary statements ]

P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
[Hazard Codes ]

C,T
[Risk Statements ]

R34:Causes burns.
R35:Causes severe burns.
R43:May cause sensitization by skin contact.
R39/23/24/25:Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R10:Flammable.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[RIDADR ]

UN 3286 3/PG 2
[WGK Germany ]

1
[RTECS ]

GA4025500
[F ]

8-9-23
[TSCA ]

Yes
[REACH Registrations]

Active
[HazardClass ]

8
[PackingGroup ]

II
[HS Code ]

29231000
[Storage Class]

3 - Flammable liquids
[Hazard Classifications]

Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Carc. 1B
Eye Dam. 1
Flam. Liq. 3
Skin Corr. 1A
STOT SE 1
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethanol-->Diethyl ether-->Isopropyl alcohol-->2-Chloroethanol-->Trimethylamine-->Silver oxide-->ACETALDEHYDE AMMONIA-->AMBERLITE(R) IRA-400 (CL)
[Preparation Products]

Monoethanolamine-->Choline chloride-->CHOLINE THIEOPHYLLINATE-->Aclatonium napadisilate-->Choline salicylate
Questions And AnswerBack Directory
[Description]

Choline hydroxide or choline base is also known as 2-hydroxyl ethyl trimethyl ammonium hydroxide. It is a strong yet organic base.
Choline hydroxide is primarily used to produce other choline salts, which could be used in nutraceuticals, baby food, etc.  Choline hydroxide can be used as phase transfer catalysts which carry the hydroxide ion into organic systems. It is used as an ingredient in cleaning and developer formulations in the electronics and printed circuit board industry and in paint stripping formulations. It can also be used as corrosion inhibitor, for the H2S removal from gas streams. Furthermore, it is used as the cleaning and degreasing agent in the metal industry.
[References]

[1] Patent US20160068476: Process for choline hydroxide
[2] https://en.wikipedia.org/wiki/Choline
Hazard InformationBack Directory
[Chemical Properties]

clear light yellow viscous solution
[Uses]

Choline hydroxide is used as a precursor molecule for the neurotransmitter acetylcholine, it is involved in several functions including muscle and memory muscle control. It was used as a basic catalyst for aldol condensation reactions.
[Definition]

An amino alcohol,CH2OHCH2N(CH3)3OH. It occurswidely in living organisms as aconstituent of certain types ofphospholipids– the lecithins andsphingomyelins– and in the neurotransmitteracetylcholine. It issometimes classified as a memberof the vitamin B complex.
[Flammability and Explosibility]

Nonflammable
[Synthesis]

A method for preparing high purity choline from choline chloride, said method being carried out in the following steps:

1) pretreating a strongly acidic cation exchange resin, said pretreatment process being: acid treatment, ultrapure water treat

[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

Choline hydroxide(123-41-1)1HNMR
Choline hydroxide(123-41-1)IR1
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Choline hydroxide, pure(123-41-1)
[Alfa Aesar]

Choline hydroxide, 46% w/w aq. soln.(123-41-1)
[Sigma Aldrich]

123-41-1(sigmaaldrich)
[TCI AMERICA]

Choline  (48-50% in Water)(123-41-1)
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