| Identification | Back Directory | [Name]
N-[4-[(2-Methoxyethyl)methylamino]phenyl]-2-phenyl-5-(trifluoromethyl)-4-oxazolecarboxamide | [CAS]
1231243-91-6 | [Synonyms]
N-[4-[(2-Methoxyethyl)methylamino]phenyl]-2-phenyl-5-(trifluoromethyl)-4-oxazolecarboxamide
N-(4-((2-Methoxyethyl)(Methyl)aMino)phenyl)-2-phenyl-5-(trifluoroMethyl)oxazole-4-carboxaMide
4-Oxazolecarboxamide, N-[4-[(2-methoxyethyl)methylamino]phenyl]-2-phenyl-5-(trifluoromethyl)-
N-{4-[(2-Methoxyethyl)(Methyl)aMino]phenyl}-2-phenyl-5-(trifluoroMethyl)-1,3-oxazole-4-carboxaMide | [Molecular Formula]
C21H20F3N3O3 | [MDL Number]
MFCD16620390 | [MOL File]
1231243-91-6.mol | [Molecular Weight]
419.4 |
| Chemical Properties | Back Directory | [density ]
1.308±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMF: 3 mg/ml,DMSO: 2 mg/ml,Ethanol: Slightly soluble,PBS (pH 7.2): 0.2 mg/ml | [form ]
A solid | [pka]
9.97±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
DGAT-1 inhibitor 3 (compound 10) is a potent DGAT-1 inhibitor with an IC50 value of 0.038 μM. DGAT-1 inhibitor 3 has the potential for the research of obesity and diabetes[1]. | [storage]
-20°C | [References]
[1] Qian Y, et al. Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetes. J Med Chem. 2011 Apr 14;54(7):2433-46. DOI:10.1021/jm101580m |
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SynAsst Chemical.
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021-60343070 |
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www.chemicalbook.com/ShowSupplierProductsList15848/0_EN.htm |
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