| Chemical Properties | Back Directory | [Boiling point ]
607.8±55.0 °C(Predicted) | [density ]
1.53±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:125.0(Max Conc. mg/mL);298.04(Max Conc. mM) | [form ]
Solid | [pka]
15.94±0.50(Predicted) | [color ]
White to off-white | [InChIKey]
HHXCJIMPEJSJTG-JTQLQIEISA-N | [SMILES]
C(N)(=O)[C@@H](NCC1=NC2=CC=C(OC3=CC(F)=C(F)C(F)=C3)N=C2N1C1CCC1)C |
| Hazard Information | Back Directory | [Uses]
DSP-2230 is a selective Nav1.7/Nav1.8 blocker, can be used to improve neuropathic pain[1][2][3]. | [IC 50]
Nav1.7; Nav1.8 | [storage]
Store at -20°C | [References]
[1] Bagal SK, et al. Voltage gated sodium channels as drug discovery targets. Channels (Austin). 2015;9(6):360-6. DOI:10.1080/19336950.2015.1079674
[2] Sara Sabina Hadida-Ruah, et al. Sulfonamides as modulators of sodium channels.
[3] Matthew Alsaloum, et al. Status of peripheral sodium channel blockers for non-addictive pain treatment. Nat Rev Neurol. 2020 Dec;16(12):689-705. DOI:10.1038/s41582-020-00415-2 |
|
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|