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1237826-25-3

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1237826-25-3 Structure

1237826-25-3 Structure
IdentificationBack Directory
[Name]

Everolimus EP Impurity E
[CAS]

1237826-25-3
[Synonyms]

Formyl Sirolimus
Everolimus EP Impurity E
(1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,-32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexyl formate
23,27-Epoxy(7E,15E,17E,19E)-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 3-[(1R)-2-[(1S,3R,4S)-4-(formyloxy)-3-methoxycyclohexyl]-1-methylethyl]-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-...
[Molecular Formula]

C52H79NO14
[MOL File]

1237826-25-3.mol
[Molecular Weight]

942.18
Chemical PropertiesBack Directory
[Boiling point ]

974.9±75.0 °C(Predicted)
[density ]

1.18±0.1 g/cm3(Predicted)
[pka]

10.40±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

42-O-Formyl Rapamycin is a derivative of Rapamycin (R124000). Rapamycin is a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. It is used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. It has shown its efficacy against neurodegenerative diseases including Alzheimer''s and Parkinson''s.
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