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141392-23-6

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141392-23-6 Structure

141392-23-6 Structure
IdentificationBack Directory
[Name]

Rapamycin, 32-O-demethyl-
[CAS]

141392-23-6
[Synonyms]

32-O-Demethyl-rapamycin
Rapamycin, 32-O-demethyl-
Rapamycin, 32-O-demethyl- (9CI)
32-O-Demethyl-rapamycin DISCONTINUED
[Molecular Formula]

C50H77NO13
[MOL File]

141392-23-6.mol
[Molecular Weight]

900.16
Chemical PropertiesBack Directory
[Boiling point ]

974.8±75.0 °C(Predicted)
[density ]

1.20±0.1 g/cm3(Predicted)
[pka]

10.40±0.70(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

GHS hazard pictograms
GHS08
[Signal word ]

Warning
[Hazard statements ]

H341
[Precautionary statements ]

P201-P202-P281-P308+P313-P405-P501
Hazard InformationBack Directory
[Uses]

27-O-Demethylrapamycin, a Rapamycin (HY-10219) derivative, is an antifungal agent. 27-O-Demethylrapamycin inhibits Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum[1].
[References]

[1] Wong GK, et al. Antifungal activities of rapamycin and its derivatives, prolylrapamycin, 32-desmethylrapamycin, and 32-desmethoxyrapamycin. J Antibiot (Tokyo). 1998 May;51(5):487-91. DOI:10.7164/antibiotics.51.487
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