| Identification | Back Directory | [Name]
E3 ligase Ligand-Linker Conjugates 33 Hydrochloride | [CAS]
1239866-59-1 | [Synonyms]
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride
E3 ligase Ligand-Linker Conjugates 33 Hydrochloride | [Molecular Formula]
C35H44ClN3O7 | [MDL Number]
MFCD32197262 | [MOL File]
1239866-59-1.mol | [Molecular Weight]
654.2 |
| Hazard Information | Back Directory | [Uses]
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 Hydrochloride can be used to design SNIPERs[1]. | [IC 50]
cIAP1 | [References]
[1] Itoh Y, et al. Protein knockdown using methyl bestatin-ligand hybrid molecules: design and synthesis of inducers of ubiquitination-mediated degradation of cellular retinoic acid-binding proteins. J Am Chem Soc. 2010 Apr 28;132(16):5820-6. DOI:10.1021/ja100691p |
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