| Identification | Back Directory | [Name]
AS 1938909 | [CAS]
1243155-40-9 | [Synonyms]
AS 1938909
3-[(2,4-dichlorophenyl)methoxy]-N-[(2,6-difluorophenyl)methyl]thiophene-2-carboxamide | [Molecular Formula]
C19H13Cl2F2NO2S | [MDL Number]
MFCD28160329 | [MOL File]
1243155-40-9.mol | [Molecular Weight]
428.28 |
| Hazard Information | Back Directory | [Description]
AS1938909 is a SHIP2 inhibitor. It acts by increasing Akt phosphorylation, glucose consumption, and glucose uptake in L6 myotubes, specifically upregulating the GLUT1 gene. | [Uses]
AS1938909 is a compound that inhibits SHIP2 activity. It can selectively inhibit SHIP2, increase Akt phosphorylation, and regulate glucose metabolism. Its effect is related to upregulating GLUT1 gene expression. | [References]
[1] Glucose metabolism activation by SHIP2 inhibitors via up-regulation of GLUT1 gene in L6 myotubes DOI:10.1016/j.ejphar.2010.06.002 |
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