| Identification | Back Directory | [Name]
CP-690550A | [CAS]
1243290-37-0 | [Synonyms]
550A
CP-690
CP-690550A
UNII-Q7ZOK859UK
CP690550A,CP 690550A
Tofatinib Impurity 31
Tofacitinib metabolite M2
Ethanone, 2-hydroxy-1-[(3R,4R)-4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]- | [Molecular Formula]
C15H21N5O2 | [MOL File]
1243290-37-0.mol | [Molecular Weight]
303.36 |
| Hazard Information | Back Directory | [Uses]
CP-690550A is an analogue of Tofacitinib (HY-40354). CP-690550A is a dual inhibitor of JAK2 and JAK3[1]. | [References]
[1] Chrencik JE, et al. Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6. J Mol Biol. 2010 Jul 16;400(3):413-33. DOI:10.1016/j.jmb.2010.05.020 |
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