| Identification | Back Directory | [Name]
Enadoline | [CAS]
124378-77-4 | [Synonyms]
Enadoline
Enadoline [inn]
Unii-kjl283326c
Enadoline
(CI 977
4-Benzofuranacetamide, N-methyl-N-((5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)-
N-[(5R,7S,8S)-7α-(1-Pyrrolidinyl)-1-oxaspiro[4.5]decane-8β-yl]-N-methylbenzofuran-4-acetamide
N-[[5R,7S,8S,(+)]-7α-(1-Pyrrolidinyl)-1-oxaspiro[4.5]decan-8β-yl]-N-methylbenzofuran-4-acetamide
N-[[5R,7S,8S,(-)]-7α-(1-Pyrrolidinyl)-1-oxaspiro[4.5]decane-8β-yl]-N-methylbenzofuran-4-acetamide
2-(Benzofuran-4-yl)-N-methyl-N-((5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl)acetamid
2-(Benzofuran-4-yl)-N-methyl-N-((5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl)acetamide
4-Benzofuranacetamide, N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)-, (5R-(5alpha,7alpha,8beta))- | [Molecular Formula]
C24H32N2O3 | [MDL Number]
MFCD00897252 | [MOL File]
124378-77-4.mol | [Molecular Weight]
396.52 |
| Hazard Information | Back Directory | [Uses]
Enadoline is a selective kappa opioid agonist. It exhibits antihyperalgesic and antiallodynic properties. | [Brand name]
Analgesic. | [in vivo]
Enadoline (i.v.; dose of e 15 min before surgery; male Sprague-Dawley rats) dose-dependently (1-100 μg/kg) blocks the development of thermal hyperalgesia as well as static and dynamic allodynia for over 24 h with respective MEDs (minimum effective doses) of < or = 1, 10 and 10 μg/kg[2]. |
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Matrix Scientific
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803 788-9494 All other calls |
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www.matrixscientific.com |
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