| Identification | Back Directory | [Name]
Bz-Tz-NHS | [CAS]
1244040-64-9 | [Synonyms]
Tz-NHS
Bz-Tz-NHS
Benzylaminotetrazine-NHS
Tetrazine-Ph-NHCO-C3-NHS ester
Tetrazine-Ph-NHCO-C3-NHS ester,Bz-Tz-NHS
Benzylamino tetrazine N-hydroxysuccinimidyl ester
5-(4-(1,2,4,5-tetrazin-3-yl)benzylamino)-5-oxopentanoic acid succinimidyl ester
2,5-Dioxo-1-pyrrolidinyl 5-[4-(1,2,4,5-tetrazin-3-yl)benzylamino]-5-oxopentanoate
2,5-dioxopyrrolidin-1-yl 5-((4-(1,2,4,5-tetrazin-3-yl)benzyl)amino)-5-oxopentanoate
2,5-Dioxo-1-pyrrolidinyl 5-[4-(1,2,4,5-tetrazin-3-yl)benzylamino]-5-oxopentanoate >=90%
5-Oxo-5-[[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl]amino]pentanoic acid 2,5-dioxo-1-pyrrolidinyl ester
Pentanoic acid, 5-oxo-5-[[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl]amino]-, 2,5-dioxo-1-pyrrolidinyl ester
Tetrazine Ph NHCO C3 NHS ester,Inhibitor,inhibit,Tetrazine-Ph-NHCO-C-3-NHS ester,TetrazinePhNHCOC3NHS ester,PROTAC Linkers
5-Oxo-5-[[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl]amino]pentanoic acid 2,5-dioxo-1-pyrrolidinyl ester, Benzylamino tetrazine N-hydroxysuccinimidyl ester, Benzylaminotetrazine-NHS, Bz-Tz-NHS | [Molecular Formula]
C18H18N6O5 | [MDL Number]
MFCD32067811 | [MOL File]
1244040-64-9.mol | [Molecular Weight]
398.373 |
| Chemical Properties | Back Directory | [density ]
1.45±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO : 100 mg/mL (251.02 mM; Need ultrasonic) | [form ]
Solid | [pka]
14.57±0.46(Predicted) | [color ]
Pink to red | [InChI]
1S/C18H18N6O5/c25-14(2-1-3-17(28)29-24-15(26)8-9-16(24)27)19-10-12-4-6-13(7-5-12)18-22-20-11-21-23-18/h4-7,11H,1-3,8-10H2,(H,19,25) | [InChIKey]
QDUUJWMNSUXICN-UHFFFAOYSA-N | [SMILES]
O=C(CCCC(ON1C(CCC1=O)=O)=O)NCC(C=C2)=CC=C2C3=NN=CN=N3 |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Uses]
Succinimidyl ester functionalized tetrazine for inverse electron demand Diels-Alder cycloaddition reactions. Succinimidyl ester will react with amines for small molecule, biomolecule or surface modification. Tetrazine will react with strained alkenes such as transcyclooctene, norbornene and cyclopropene to yield a stable covalent linkage. Tetrazines have proven useful in bioorthogonal reactions for many biological imaging and bioconjugation applications. | [reaction suitability]
reaction type: click chemistry
reagent type: linker | [IC 50]
PEGs |
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