| Identification | Back Directory | [Name]
6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide | [CAS]
1248581-07-8 | [Synonyms]
PTC725
6-(3-cyano-6-ethyl-5-fluoro-1-pyrimidin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide | [Molecular Formula]
C23H18F4N6O2S | [MDL Number]
MFCD28902179 | [MOL File]
1248581-07-8.mol | [Molecular Weight]
518.49 |
| Hazard Information | Back Directory | [Description]
PTC725 is a selective inhibitor of HCV 1b (Con 1) replicon. It has been shown to target the nonstructural protein 4B (NS4B). | [Uses]
PTC 725 is a potent, selective and orally active Hepatitis C Virus NS4B Protein inhibitor. PTC 725 inhibits HCV 1b (Con1) replicons[1]. | [References]
[1] Gu Z, et al. Identification of PTC725, an orally bioavailable small molecule that selectively targets the hepatitis C Virus NS4B protein. Antimicrob Agents Chemother. 2013 Jul;57(7):3250-61. DOI:10.1128/AAC.00527-13 |
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