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1250773-62-6

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1250773-62-6 Structure

1250773-62-6 Structure
IdentificationBack Directory
[Name]

2,2-Difluoro-2-(2-methoxyphenyl)acetic Acid
[CAS]

1250773-62-6
[Synonyms]

Difluoro(2-methoxyphenyl)acetic acidê
2,2-Difluoro-2-(2-methoxyphenyl)acetic Acid
Benzeneacetic acid, α,α-difluoro-2-methoxy-
[Molecular Formula]

C9H8F2O3
[MDL Number]

MFCD16748867
[MOL File]

1250773-62-6.mol
[Molecular Weight]

202.16
Chemical PropertiesBack Directory
[Boiling point ]

310.9±42.0 °C(Predicted)
[density ]

1.324±0.06 g/cm3(Predicted)
[pka]

1.06±0.10(Predicted)
Safety DataBack Directory
[HS Code ]

2918999090
Hazard InformationBack Directory
[Synthesis]

2,2-Difluoro-2-(2-methoxyphenyl)acetic Acid is primarily used to introduce benzylic difluoromethylene group to molecular scaffolds through radical decarboxylative reaction. The reaction begins with an oxidative decarboxylation with persulfate forming a difluorobenzyl radical that is stabilized by the benzene and fluorine groups. The addition is carried out by the attack of the radical species to the alkenes or imines.
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