| Identification | Back Directory | [Name]
Bayer-18 | [CAS]
1251752-12-1 | [Synonyms]
Bayer-18
BAYER18;BAYER 18
Bayer-18 (TYK Tool 2)
1-(tert-Butyl)-3-(3-((5-fluoro-4-((1-hydroxy-2-methylpropan-2-yl)amino)pyrimidin-2-yl)amino)ph
1-(tert-Butyl)-3-(3-((5-fluoro-4-((1-hydroxy-2-methylpropan-2-yl)amino)pyrimidin-2-yl)amino)phenyl)urea
N-(1,1-Dimethylethyl)-N'-[3-[[5-fluoro-4-[(2-hydroxy-1,1-dimethylethyl)amino]-2-pyrimidinyl]amino]phenyl]urea
Urea, N-(1,1-diMethylethyl)-N'-[3-[[5-fluoro-4-[(2-hydroxy-1,1-diMethylethyl)aMino]-2-pyriMidinyl]aMino]phenyl]- | [Molecular Formula]
C19H27FN6O2 | [MDL Number]
MFCD21608462 | [MOL File]
1251752-12-1.mol | [Molecular Weight]
390.46 |
| Chemical Properties | Back Directory | [density ]
1.283±0.06 g/cm3(Predicted) | [solubility ]
DMSO: Sparingly Soluble: 1-10 mg/ml
Ethanol: Sparingly Soluble: 1-10 mg/ml | [form ]
Solid | [pka]
14.08±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Bayer 18 is a Tyk2 inhibitor, useful for the treatment of a variety of inflammatory diseases. | [IC 50]
Tyk2 | [References]
[1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras. |
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