| Identification | Back Directory | [Name]
N-BOC-SERINOL, 97 | [CAS]
125414-41-7 | [Synonyms]
N-Boc-serinol 97%
N-BOC-SERINOL, 97
2-(Boc-amino)-1,3-propanediol
tert-Butyl (1,3-dihydroxypropan-2-yl)
t-Butyl 1,3-dihydroxypropan-2-ylcarbamate
tert-Butyl (1,3-dihydroxypropan-2-yl)carbaMate
tert-butyl N-[2-hydroxy-1-(hydroxymethyl)ethyl]carbamate
Carbamic acid, [2-hydroxy-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester
CarbaMic acid,N-[2-hydroxy-1-(hydroxyMethyl)ethyl]-, 1,1-diMethylethyl ester | [Molecular Formula]
C8H17NO4 | [MDL Number]
MFCD00270213 | [MOL File]
125414-41-7.mol | [Molecular Weight]
191.22 |
| Chemical Properties | Back Directory | [Melting point ]
85-89 °C
| [Boiling point ]
363.0±32.0 °C(Predicted) | [density ]
1.136±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
Solid | [pka]
11.60±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
T-Butyl 1,3-dihydroxypropan-2-ylcarbamate is a branched PEG derivative with biotin and two hydroxyl moieties. The hydroxyl groups enable further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine. | [Uses]
N-Boc-serinol is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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