| Identification | More | [Name]
Gossypol-acetic acid | [CAS]
12542-36-8 | [Synonyms]
1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde-acetic acid
GOSSYPOL ACETATE
GOSSYPOL-ACETIC ACID
aceticacidgossypol
Gossypolaceticacidcomplex
GOSSYPOL ACETATE 98%
GOSSYPOLMONOACETICACID
1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde-acetic acid
GOSSYPOLACETATE(GOSSYPOL-ACETICACID) | [EINECS(EC#)]
623-939-3 | [Molecular Formula]
C32H34O10 | [MDL Number]
MFCD00058385 | [Molecular Weight]
578.61 | [MOL File]
12542-36-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
164-168°C | [storage temp. ]
−20°C
| [solubility ]
Soluble in acetone or methanol at 5mg/ml | [form ]
neat | [color ]
Yellow to Very Dark Yellow | [Major Application]
food and beverages | [InChIKey]
NIOHNDKHQHVLKA-UHFFFAOYSA-N | [SMILES]
C12C(C(C)C)=C(C(O)=C(C=O)C=1C(O)=C(C1C(C)=CC3C(C(C)C)=C(O)C(O)=C(C=O)C=3C=1O)C(C)=C2)O.C(=O)(O)C | [LogP]
6.157 (est) | [CAS DataBase Reference]
12542-36-8(CAS DataBase Reference) | [EPA Substance Registry System]
12542-36-8(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S22:Do not breathe dust .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
MD7360000
| [HS Code ]
29153900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Carc. 2 |
| Hazard Information | Back Directory | [Chemical Properties]
Derived from the seeds and root bark of Gossypium herbaceum L., a plant of the Malvaceae family | [Uses]
Gossypol is a mixture of natural polyphenols isolated from the cotton plant. It causes spermatogenesis arrest in humans and also functions as an anti-malarial agent. Antiinflammatory. Anticancer. | [Biochem/physiol Actions]
Reported to inhibit the autolytic conversion of pepsinogen to pepsin. | [IC 50]
Bcl-xL: 0.5-0.6 μM (Ki); Bcl-2: 0.2-0.3 mM (Ki) |
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