| Identification | Back Directory | [Name]
Cholesterol sulfate | [CAS]
1256-86-6 | [Synonyms]
Cholesterol sulfate
Cholesterol 3-sulfate
3β-Cholesteryl sulfate
Cholesterol sulfuric acid
Cholesterol 3-sulfuric acid
Cholesterol Sulfate Triethylamine Salt
Cholest-5-en-3-ol (3β)-, hydrogen sulfate
(3beta)-Cholest-5-en-3-ol hydrogen sulfate
[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate
sulfuric acid [(3S,8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] ester | [Molecular Formula]
C27H46O4S | [MDL Number]
MFCD00870207 | [MOL File]
1256-86-6.mol | [Molecular Weight]
466.72 |
| Hazard Information | Back Directory | [Uses]
Cholesterol sulfate is a DOCK2 inhibitor. Cholesterol sulfate has an IC50 value of 2 μM for mouse DOCK2. Cholesterol sulfate can be used in studies such as immunity and inflammation[1]. | [Definition]
ChEBI: A steroid sulfate that is cholesterol substituted by a sulfoxy group at position 3. | [IC 50]
Human Endogenous Metabolite; DOCK2 | [References]
[1] Sakurai T, et al. Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye. Sci Signal. 2018 Jul 31;11(541):eaao4874. DOI:10.1126/scisignal.aao4874 |
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