| Identification | Back Directory | [Name]
15(S)-HPEPE | [CAS]
125992-60-1 | [Synonyms]
15(S)-HPEPE
FPMFSFWYWZLDKP-DBVSHIMFSA-N
15(S)-HYDROPEROXYEICOSA-5Z,8Z,11Z,13E,17Z-PENTAENOIC ACID
15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E,17Z)-EICOSAPENTAENOIC ACID
15(S)-hydroperoxy-5(Z),8(Z),11(Z),13(E),17(Z)-eicosapentaenoic acid, 100 ug
5,8,11,13,17-Eicosapentaenoic acid, 15-hydroperoxy-, (5Z,8Z,11Z,13E,15S,17Z)- | [Molecular Formula]
C20H30O4 | [MDL Number]
MFCD00065836 | [MOL File]
125992-60-1.mol | [Molecular Weight]
334.45 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml | [form ]
Clear to light-yellow liquid. |
| Hazard Information | Back Directory | [Uses]
15(S)-HpEPE is a product of lipoxygenase hydrolysis of unsaturated fatty acids (PUFA) and is a potential inhibitor of prostaglandin H synthase 2 (PGHS-2). 15(S)-HpEPE can downregulate the expression of PGHS-2[1]. | [References]
[1] Ait-Said F, et al. Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: involvement of lipoxygenase-derived metabolites and p38 MAPK pathway. Biochim Biophys Acta. 2003 Feb 20;1631(1):77-84. DOI:10.1016/s1388-1981(02)00358-x |
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| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
|