| Identification | Back Directory | [Name]
(±)-5-HETE, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution | [CAS]
71030-39-2 | [Synonyms]
KGIJOOYOSFUGPC-XTDASVJISA-N
(±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution
6,8,11,14-Eicosatetraenoic acid, 5-hydroxy-, (6E,8Z,11Z,14Z)-
(±)-5-HETE, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution | [Molecular Formula]
C20H32O3 | [MDL Number]
MFCD00065818 | [MOL File]
71030-39-2.mol | [Molecular Weight]
320.47 |
| Chemical Properties | Back Directory | [Boiling point ]
487.7±45.0 °C(Predicted) | [density ]
0.984±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
0.1 M Na2CO3: 2 mg/ml
DMF: Miscible
DMSO: Miscible
Ethanol: MisciblePBS pH 7.2: 0.8 mg/ml | [form ]
Liquid | [pka]
4.67±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC50 value of 200 nM[1]. | [Definition]
ChEBI: 5-HETE is a HETE having a 5-hydroxy group and (6E)-, (8Z)-, (11Z)- and (14Z)-double bonds. It has a role as a mouse metabolite. It is a conjugate acid of a 5-HETE(1-). | [References]
[1] J T O'Flaherty, et al. Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids. Am J Pathol. 1981 Jul;104(1):55-62. PMID:7258296 |
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