| Identification | Back Directory | [Name]
Benzamide, N-cyclopropyl-4-[8-[(2-methylpropyl)amino]imidazo[1,2-a]pyrazin-3-yl]- | [CAS]
1263420-68-3 | [Synonyms]
Mps-BAY2b
Benzamide, N-cyclopropyl-4-[8-[(2-methylpropyl)amino]imidazo[1,2-a]pyrazin-3-yl]- | [Molecular Formula]
C20H23N5O | [MOL File]
1263420-68-3.mol | [Molecular Weight]
349.43 |
| Hazard Information | Back Directory | [Description]
Mps-BAY2b is a novel inhibitor of MPS1. | [Uses]
Mps-BAY2b is a oral active monopolar spindle 1 (MPS1) inhibitor with the IC50 of 14 nM (human MPS1). Mps-BAY2b shows anticancer activity and can be used for study of cancer[1]. | [References]
[1] Jemaà M, et al. Characterization of novel MPS1 inhibitors with preclinical anticancer activity. Cell Death Differ. 2013 Nov;20(11):1532-45. DOI:10.1038/cdd.2013.105 |
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