| Identification | Back Directory | [Name]
4-Thiazolidinone, 5-[(4-hydroxy-3-methylphenyl)methylene]-2-thioxo-, (5Z)- | [CAS]
1287651-36-8 | [Synonyms]
HMBR
(Z)-5-(4-hydroxy-3-methylbenzylidene)-2-thioxo-1,3-thiazolidin-4-one
4-Thiazolidinone, 5-[(4-hydroxy-3-methylphenyl)methylene]-2-thioxo-, (5Z)-
(5Z)-5-[(4-hydroxy-3-methylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one | [Molecular Formula]
C11H9NO2S2 | [MOL File]
1287651-36-8.mol | [Molecular Weight]
251.32 |
| Hazard Information | Back Directory | [Uses]
HMBR is an analogue with an additional methyl group on the aromatic ring and is non-fluorescent. HMBR conjugated with Y-FAST emits yellow fluorescence under blue light excitation (Ex= 419 nm; Em= 525–539 nm). HMBR is non-toxic to zebrafish embryos. HMBR has high cell permeability[1]. | [in vivo]
HMBR (100 μl 5 mM, oral) fluorescently activated EcN-FAST, and the intestine was collected 5 h after administration, and the overall fluorescence intensity was recorded by IVIS imaging[2]. | [References]
[1] Plamont MA, et al. Small fluorescence-activating and absorption-shifting tag for tunable protein imaging in vivo [published correction appears in Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):E1412. Moncoq, Karine [added]]. Proc Natl Acad Sci U S A. 2016;113(3):497-502. DOI:10.1073/pnas.1513094113
[2] Zhenping Cao, et al. Encoding with a fluorescence-activating and absorption-shifting tag generates living bacterial probes for mammalian microbiota imaging. Mater Today Bio. 2022 Jun 6:15:100311. DOI:10.1016/j.mtbio.2022.100311 |
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