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130100-20-8

130100-20-8 Structure

130100-20-8 Structure
IdentificationBack Directory
[Name]

MAG-FURA-2, AM
[CAS]

130100-20-8
[Synonyms]

Mag-fura-2
MAG-FURA-2, AM
MAFENIDEACETATE
Furaptra Am Ester
Magfura-2 Am Ester
Mag-Fura-2-AM, ≥95%
PCDUVTXECKTHBH-UHFFFAOYSA-N
Furaptra Acetoxymethyl Ester
Mag-Fura 2, AM Cell PerMeant
mag-fura-2-acetoxymethylester
Fura 2-AM magnesium-selective analog
FURA 2-AM magnesium selective analogue
fura 2-am analog selective for*magnesium
Furaptra, AM ester [Known as Mag-Fura-2, AM ester, TM of Molecular Probes]
acetyloxymethyl 2-[5-[2-(acetyloxymethoxy)-2-oxoethoxy]-6-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-1-benzofuran-2-yl]-1,3-oxazole-5-carboxylate
2-[5-[2-(acetoxymethoxy)-2-keto-ethoxy]-6-[bis[2-(acetoxymethoxy)-2-keto-ethyl]amino]benzofuran-2-yl]oxazole-5-carboxylic acid acetoxymethyl ester
acetyloxymethyl 2-[5-[2-(acetyloxymethoxy)-2-oxo-ethoxy]-6-[bis[2-(acetyloxymethoxy)-2-oxo-ethyl]amino]-1-benzofuran-2-yl]-1,3-oxazole-5-carboxylate
5-Oxazolecarboxylic acid, 2-[5-[2-[(acetyloxy)methoxy]-2-oxoethoxy]-6-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-2-benzofuranyl]-, (acetyloxy)methyl ester
[Molecular Formula]

C30H30N2O19
[MDL Number]

MFCD00213961
[MOL File]

130100-20-8.mol
[Molecular Weight]

722.56
Chemical PropertiesBack Directory
[Melting point ]

>200℃
[Boiling point ]

797.5±70.0 °C(Predicted)
[density ]

1.436±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

Insoluble in water; soluble in dimethyl sulfoxide, ethyl acetate
[form ]

powder
[pka]

-2.19±0.10(Predicted)
[color ]

Light yellow
[Appearance]

Solid Powder
[ex/em]

λex 330 nm; λem 491 nm
[λmax]

366 nm
[Biological Applications]

Magnesium indicator; calcium indicator; zinc indicator
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Benzene-->ethyl 2-(4-methoxyphenylamino)-2-oxoacetate
Hazard InformationBack Directory
[Description]

Mag-fura-2 AM is a membrane-permeant, short-wavelength fluorescent indicator for intracellular magnesium. It can be loaded into cells via incubation, and hydrolyzed to mag-fura-2. Intracellular magnesium concentration can be measured by ratio of fluorescence intensity generated by mag-fura-2.

[Uses]

Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues. MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions[1].
[storage]

Store at -20°C
[References]

[1] García-Martín E, et, al. Intrasynaptosomal free Mg2+ concentration measured with the fluorescent indicator mag-fura-2: modulation by Na+ gradient and by extrasynaptosomal ATP. J Neurochem. 1995 Dec;65(6):2757-64. DOI:10.1046/j.1471-4159.1995.65062757.x
[Excitation / Emission Maximum]

537 nm/559 ±5 nm
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