| Identification | Back Directory | [Name]
MAG-INDO 1-AM | [CAS]
130926-94-2 | [Synonyms]
MAG-INDO 1-AM
INDO 1-AM ANALOG
Mag-indo-1 Am Ester
MAG-INDO 1-AM, 10X50 UG*
Mag-indo-1 Acetoxymethyl Ester
indo 1-am analog selective for*magnesium | [Molecular Formula]
C30H32N2O12 | [MDL Number]
MFCD00164444 | [MOL File]
130926-94-2.mol | [Molecular Weight]
612.581 |
| Chemical Properties | Back Directory | [Melting point ]
>200℃ | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble | [form ]
powder | [color ]
Pale yellow | [λmax]
354 nm | [Biological Applications]
Magnesium indicator; calcium indicator |
| Hazard Information | Back Directory | [Description]
Mag-indo-1 AM is a membrane-permeant fluorescent indicator for intracellular magnesium. It can be loaded into cells via incubation, and hydrolyzed to mag-indo-1 by cytosilic esterases. | [Uses]
Mag-indo-1/AM is a cell-permeable fluorescent indicator for Mg2+ and also for Ca2+ (Ex=340-390 nm, Em=410-490 nm). Mag-indo-1/AM can be used to determine intracellular Mg2+ and Ca2+ concentrations[1][2]. | [References]
[1] Griffiths EJ. Calcium handling and cell contraction in rat cardiomyocytes depleted of intracellular magnesium. Cardiovasc Res. 2000 Jul;47(1):116-23. DOI:10.1016/s0008-6363(00)00061-4
[2] Morelle B, et al. Measurement of intracellular magnesium concentration in 3T3 fibroblasts with the fluorescent indicator Mag-indo-1. Anal Biochem. 1994 Apr;218(1):170-6. DOI:10.1006/abio.1994.1156 | [Excitation / Emission Maximum]
537 nm/559 ±5 nm |
|
| Company Name: |
Synchem OHG
|
| Tel: |
+49 5662 408730 |
| Website: |
www.synchem.de |
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
|