ChemicalBook--->CAS DataBase List--->131-53-3

131-53-3

131-53-3 Structure

131-53-3 Structure
IdentificationMore
[Name]

2,2'-Dihydroxy-4-methoxybenzophenone
[CAS]

131-53-3
[Synonyms]

2,2'-DIHYDROXY-4-METHOXYBENZOPHENONE
BENZOPHENONE-8
DIOXYBENZONE
LABOTEST-BB LT00159976
(2-hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)-methanon
(2-Hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)methanone
(2-hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)-Methanone
2,2’-dihydroxy-4-methoxy-benzophenon
Advastab 47
advastab47
Benzophenone, 2,2'-dihydroxy-4-methoxy-
component of Solaquin
Cyasorb
Cyasorb UV 24
Cyasorb UV 24 Light Absorber
cyasorbuv24
cyasorbuv24lightabsorber
Dioxybenzon
Methanone, (2-hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)-
Methanone,(2-hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)-
[EINECS(EC#)]

205-026-8
[Molecular Formula]

C14H12O4
[MDL Number]

MFCD00002218
[Molecular Weight]

244.24
[MOL File]

131-53-3.mol
Chemical PropertiesBack Directory
[Appearance]

yellow powder
[Melting point ]

73-75 °C(lit.)
[Boiling point ]

170-175 °C1 mm Hg(lit.)
[density ]

1.2379 (rough estimate)
[vapor pressure ]

0-0Pa at 20-25℃
[refractive index ]

1.5389 (estimate)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

neat
[pka]

7.11±0.35(Predicted)
[color ]

Off-White to Yellow
[Stability:]

Stable. Incompatible with strong oxidizing agents.
[Merck ]

3303
[Cosmetics Ingredients Functions]

UV ABSORBER
[Cosmetic Ingredient Review (CIR)]

2,2'-Dihydroxy-4-methoxybenzophenone (131-53-3)
[InChI]

1S/C14H12O4/c1-18-9-6-7-11(13(16)8-9)14(17)10-4-2-3-5-12(10)15/h2-8,15-16H,1H3
[InChIKey]

MEZZCSHVIGVWFI-UHFFFAOYSA-N
[SMILES]

COc1ccc(c(O)c1)C(=O)c2ccccc2O
[LogP]

2.33 at 23.5℃
[Uses]

benzophenone-8 (dioxybenzone) is an FDA-approved sunscreen chemical with uVA-absorption capabilities. It also can protect product degradation arising from uV-light exposure. It has an approved usage level of 3 percent in the united States.
[CAS DataBase Reference]

131-53-3(CAS DataBase Reference)
[NIST Chemistry Reference]

Dioxybenzone(131-53-3)
[EPA Substance Registry System]

131-53-3(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[RTECS ]

DJ1049500
[TSCA ]

TSCA listed
[REACH Registrations]

Active
[HS Code ]

29145090
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
[Hazardous Substances Data]

131-53-3(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Resorcinol-->Dimethyl sulfate
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

2,2'-Dihydroxy-4-methoxybenzophenone(131-53-3).msds
Hazard InformationBack Directory
[Reactivity Profile]

An alcohol and a ketone. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
[Fire Hazard]

Flash point data for this compound are not available. 2,2'-DIHYDROXY-4-METHOXYBENZOPHENONE is probably combustible.
[Chemical Properties]

Light yellow powder. Freezing point 68℃, boiling point 170-175℃(0.133kPa), relative density 1.382(25℃).Solubility at 25℃(g/100g solvent): benzene 46.6, n-hexane 2.3, 95% ethanol 21.4, carbon tetrachloride 22.2, methylethyl ketone 55.3, plasticiser DOP 31.1, insoluble in water.
[Application]

Dioxybenzone is a compound used in sunscreen formulations to block out UVB and UVA harmful rays. Broad-spectrum sunscreens often contain a number of chemical ingredients that absorb UVA and UVB radiation. Many sunscreens contain UVA-absorbing avobenzone or a benzophenone (such as dioxybenzone, oxybenzone, or sulisobenzone), in addition to UVB-absorbing chemical ingredients (some of which also contribute to UVA protection).
[Definition]

ChEBI: 2,2'-Dihydroxy-4-methoxybenzophenone is a member of benzophenones.
[Preparation]

preparation by condensation of salicylic acid and m-methoxyphenol.
[General Description]

Dioxybenzone, or benzophenone-8, is an organic compound derived from Benzophenone that is used as a sunscreen agent. It absorbed UV-B and UV-AII rays. Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3%.
Spectrum DetailBack Directory
[Spectrum Detail]

2,2'-Dihydroxy-4-methoxybenzophenone(131-53-3)1HNMR
2,2'-Dihydroxy-4-methoxybenzophenone(131-53-3)13CNMR
2,2'-Dihydroxy-4-methoxybenzophenone(131-53-3)IR1
2,2'-Dihydroxy-4-methoxybenzophenone(131-53-3)Raman
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

131-53-3(sigmaaldrich)
[TCI AMERICA]

2,2'-Dihydroxy-4-methoxybenzophenone,>97.0%(GC)(131-53-3)
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