ChemicalBook--->CAS DataBase List--->131068-47-8

131068-47-8

131068-47-8 Structure

131068-47-8 Structure
IdentificationBack Directory
[Name]

SUC-ALA-ALA-PRO-ARG-PNA
[CAS]

131068-47-8
[Synonyms]

SUC-AAPR-PNA
Suc-AAPD -pNA
SUC-ALA-ALA-PRO-ARG-PNA
N-(3-Carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-argininamide
L-Argininamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-
[Molecular Formula]

C27H39N9O9
[MDL Number]

MFCD00238354
[MOL File]

131068-47-8.mol
[Molecular Weight]

633.65
Chemical PropertiesBack Directory
[density ]

1.50±0.1 g/cm3(Predicted)
[storage temp. ]

-15°C
[pka]

4.69±0.10(Predicted)
[Sequence]

{Suc-Ala}-Ala-Pro-{Arg-pNA}
Hazard InformationBack Directory
[Uses]

Suc-AAPR-pNA is a substrate of trypsin acyl-enzymes. Suc-AAPR-pNA can be used to test trypsin acyl-enzymes activity[1][2].
[References]

[1] DeSantis G, et, al. Toward tailoring the specificity of the S1 pocket of subtilisin B. lentus: chemical modification of mutant enzymes as a strategy for removing specificity limitations. Biochemistry. 1999 Oct 5;38(40):13391-7. DOI:10.1021/bi990861o
[2] Radisky ES, et, al. Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates. Proc Natl Acad Sci U S A. 2006 May 2;103(18):6835-40. DOI:10.1073/pnas.0601910103
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