| Identification | Back Directory | [Name]
3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide | [CAS]
1316059-00-3 | [Synonyms]
159344
3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide
Benzenesulfonamide, 3-[[6-[(5-chloro-2-pyridinyl)amino]-4-pyrimidinyl]amino]-4-(ethylsulfonyl)-N-methyl- | [Molecular Formula]
C18H19ClN6O4S2 | [MDL Number]
MFCD29919171 | [MOL File]
1316059-00-3.mol | [Molecular Weight]
482.96 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 250 mg/mL (517.64 mM; Need ultrasonic) | [form ]
Solid | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
GSK854 is a potent Inhibitor of Troponin I-Interacting Kinase (TNNI3K). GSK854 is a suitable lead for identifying new cardiac medicines and have been employed as in vivo tools in investigational studies aimed at defining the role of TNNI3K within heart failure[1]. | [Biological Activity]
GSK854 is a potent Inhibitor of Troponin I-Interacting Kinase (TNNI3K). GSK854 is a suitable lead for identifying new cardiac medicines and have been employed as in vivo tools in investigational studies aimed at defining the role of TNNI3K within heart failure[1]. | [storage]
Store at -20°C | [References]
[1]. Philp J, et al. 4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase (TNNI3K) Inhibitors. J Med Chem. 2018;61(7):3076-3088. |
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ChemShuttle, Inc.
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0510-83588313-811 18800520310 |
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www.jiehuapharma.com/ |
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