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1316189-13-5

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1316189-13-5 Structure

1316189-13-5 Structure
IdentificationBack Directory
[Name]

MPEG8-NHS
[CAS]

1316189-13-5
[Synonyms]

MPEG8-NHS
m-PEG9-NHS ester
m-PEG8-CH2CH2-NHS ester
mPEG8-CH2CH2COONHS Ester
2,5-Dioxo-1-pyrrolidinyl 4,7,10,13,16,19,22,25,28-nonaoxanonacosanoate
4,7,10,13,16,19,22,25,28-Nonaoxanonacosanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
[Molecular Formula]

C24H43NO13
[MDL Number]

MFCD20229517
[MOL File]

1316189-13-5.mol
[Molecular Weight]

553.6
Chemical PropertiesBack Directory
[Boiling point ]

598.3±60.0 °C(Predicted)
[density ]

1.20±0.1 g/cm3(Predicted)
[solubility ]

Soluble in DMSO, DCM, DMF
Hazard InformationBack Directory
[Description]

m-PEG9-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.
[Uses]

m-PEG9-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
[IC 50]

PEGs; Alkyl/ether
[References]

[1] Alexander Chucholowski, et al. Cyclodextrin conjugates. WO2010017328A2.
[2] Satwik Kamtekar, et al. Modified biotin-binding proteins for immobilization. WO2019126734A1.
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