| Identification | Back Directory | [Name]
(S)-(-)-5-Fluorowillardiine (hydrochloride) | [CAS]
1321546-70-6 | [Synonyms]
(5S)-Fluorowillardiine hydrochloride
(S)-(-)-5-Fluorowillardiine (hydrochloride) | [Molecular Formula]
C7H9ClFN3O4 | [MDL Number]
MFCD28385871 | [MOL File]
1321546-70-6.mol | [Molecular Weight]
253.61 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
Water: Soluble | [form ]
Solid | [color ]
White to off-white | [Water Solubility ]
Water: 6.67 mg/mL (26.30 mM) |
| Hazard Information | Back Directory | [Uses]
(S)-(-)-5-Fluorowillardiine hydrochloride is a potent and specific AMPAR agonist. | [storage]
Store at -20°C | [References]
[1] Hawkinson JE, et al. Effects of thiocyanate and AMPA receptor ligands on (S)-5-fluorowillardiine, (S)-AMPA and (R,S)-AMPA binding. Eur J Pharmacol. 1997 Jun 25;329(2-3):213-21. PMID:9226415
[2] Kessler M, et al. Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators. Brain Res. 2006 Mar 3;1076(1):25-41. DOI:10.1016/j.brainres.2005.09.024
[3] Rembach A, et al. Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS. J Neurosci Res. 2004 Aug 15;77(4):573-82. DOI:10.1002/jnr.20191 |
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